Enantiocontrolled Synthesis of (-)-9-epi-Pentazocine and (-)-Aphanorphine.

[摘要]：We have developed novel asym. routes to (-)-9-epi-pentazocine (I) and (-)-aphanorphine (II) from a D-tyrosine deriv. The tricyclic frameworks of (-)-9-epi-pentazocine and (-)-aphanorphine were assembled stereoselectively via intramol. Friedel-Crafts reaction of the corresponding bicyclic precursors, generated with titanium-promoted enyne cyclization and indium-initiated atom-transfer radical cyclization, resp.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内