[摘要]：A nucleic acid detection scheme that employs DNA-mediated delivery of an organomercury activator to unmask a fluorophore is described. The approach relies on adjacent hybridization of two oligonucleotide conjugates contg. organomercury and caged rhodamine functionalities. Postsynthetic conjugation of amino-modified DNAs enabled efficient prepn. of these probes. Complementary DNA templates yielded fluorescence signals arising from metal-assisted rhodamine uncaging.
