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Direct Access to Anthranilic Acid Derivatives via CO2 Incorporation Reaction Using Arynes.

  作者 Yoshida, Hiroto;Morishita, Takami;Ohshita, Joji;  
  选自 期刊  Organic Letters;  卷期  2008年10-17;  页码  3845-3847  
  关联知识点  
 

[摘要]CO2 was found to be directly convertible into anthranilic acid derivs. of great synthetic value through a three-component coupling using arynes and secondary amines. Zwitterions arising from nucleophilic attack of amines to arynes serve as key intermediates in the coupling.

 
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