Whole structure-activity relationships of the fat-accumulation inhibitor (-)-ternatin: Recognition of the importance of each amino acid residue.

[摘要]：A series of Ala and Aoc (Ala = alanine; Aoc = 2-aminooctane carboxylic acid) analogs of (-)-ternatin were prepd., and their bioactivities were assessed by a fat-accumulation inhibition assay using 3T3-L1 adipocytes, which led to the discovery of key structure-activity relationships (SAR).

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