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[摘要]:An efficient synthesis of an array of poly-substituted quinolines from 2-aminoaryl ketones and b-ketoester, b-diketones and a-methylene ketones using KAl(SO4)2?2H2O-SiO2 (Alum-SiO2) under solvent-free conditions is described. Compared with the classical Friedlander synthesis this new synthetic method has the advantage of excellent yields (90-98%), shorter reaction time, and reusability of the catalyst. |
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