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Synthesis of nitrogen heterocycles by intramolecular cyclization of alkenyl N-acylaminophthalimides using phenyliodine(III) bis(trifluoroacetate) (PIFA).

  作者 Tsukamoto, Masato;Murata, Kousuke;Sakamoto, Takeshi;Saito, Setsuo;Kikugawa, Yasuo;  
  选自 期刊  Heterocycles;  卷期  2008年75-5;  页码  1133-1149  
  关联知识点  
 

[摘要]PIFA-mediated intramol. cyclization of alkenyl N-acylaminophthalimides leads to the formation of a new C-N bond via an N-acyl-N-phthalimidonitrenium ion intermediate. The reaction pathway also results in the introduction of an oxygen function into the mol. giving added versatility to this single step procedure.

 
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