[摘要]：Macrocyclic ligands contg. two 5-mercapto-3H-1,3,4-thiadiazoline-2-one groups and one 1,3-benzenedimethanethiol group, which served to link the 2- and 5-positions of the heterocycle unit and chelate palladium ion, resp., were synthesized by regiospecific S-alkylation of 5-ethoxy-3H-1,3,4-thiadiazoline-2-thione. Structures of the resulting metalloreceptors were established using 1H and 13C NMR, FTIR spectroscopy, MS spectrometry, and elemental anal. The mol. recognition ability of the metalloreceptors was examd. against DNA/RNA nucleobases and acetanilide. The complexation strength of both compds. increased in the order acetanilide/uracil/thymine < adenine < cytosine.
