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Synthesis of chiral (sulfinyl)furyl oxazoline ligands and its application to enantioselective palladium-catalyzed allylic alkylation.

  作者 Bunya, Yusuke;Sengoku, Takaaki;Imamura, Yoko;Arai, Yoshitsugu;  
  选自 期刊  Heterocycles;  卷期  2008年76-1;  页码  833-843  
  关联知识点  
 

[摘要]Chiral ligands contg. an oxazoline substituent and a sulfur functionality at the furan ring were synthesized and examd. for enantioselective Pd-catalyzed allylic substitution reaction. The enantioselectivity obsd. was dependent on the nature of the S center and oxazoline group, giving ?1% ee with a chiral 3-sulfinylfur-2-yl ligand.

 
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