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The regioselective synthesis of 2H-pyrido[2,3-b]pyrrolo[2,3-e]pyrazin-2-one.

  作者 Jamrozy, Krzysztof;Szymoniak, Katarzyna;Ostrowska, Katarzyna;  
  选自 期刊  Heterocycles;  卷期  2008年75-9;  页码  2275-2282  
  关联知识点  
 

[摘要]Compounds (More Than One Hetero Atom)) Section The regioselective reaction of 1-aryl-4-(phenylhydroxymethylidene)-pyrrolidine-2,3,5-triones, e.g., I, with 2,3-diaminopyridine in boiling glacial AcOH in the presence of TsOH led to the formation of new 2H-pyrido[2,3-b]pyrrolo[2,3-e]pyrazin-2-ones, e.g., II. The structure of this fused heterocyclic system was confirmed by IR, 1D and 2D NMR expts.

 
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