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Synthesis of pyrrolo[2,3-d]pyrimidine analogues of the potent antitumor agent N-{4-[3-(2,4-diamino-7H-pyrrolo-[2,3-d]pyrimidin-5-yl)propyl]benzoyl}-L- glutamic acid (TNP-351).

  作者 Zhu, Gaojun;Liu, Zenglu;Xu, Yun;Mao, Zhenmin;  
  选自 期刊  Heterocycles;  卷期  2008年75-7;  页码  1631-1638  
  关联知识点  
 

[摘要]Two glutamate derivs. I and II, analogs of TNP-351, of were synthesized as anticancer agents, and their biol. activities were evaluated.

 
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