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New strategies for the synthesis of pyrimidine derivatives.

  作者 Hill, Matthew D.;Movassaghi, Mohammad;  
  选自 期刊  Chemistry-A European Journal;  卷期  2008年14-23;  页码  6836-6844  
  关联知识点  
 

[摘要]A review. Recent advances in pyrimidine synthesis are described. Modification of conventional strategies involving N-C-N fragment condensation with 1,3-dicarbonyl derivs. remains a common theme in current literature. Other methods, including N-C fragment condensation strategies, provide reactive intermediates capable of intramol. cyclization and formation of pyrimidine derivs. These recently developed methodologies offer a valuable addendum to azaheterocycle synthesis.

 
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