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Stable and potent polyvalent anthrax toxin inhibitors: raft-inspired domain formation in liposomes that contain PEGylated lipids.

  作者 Rai, Prakash;Vance, David;Poon, Vincent;Mogridge, Jeremy;Kane, Ravi S.;  
  选自 期刊  Chemistry-A European Journal;  卷期  2008年14-26;  页码  7748-7751  
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[摘要]A raft of inspiration: We report the synthesis of highly active and stable polyvalent anthrax toxin inhibitors based on laterally phase-sepd. PEGylated liposomes. Heterogeneous domain-contg. PEGylated liposomes are considerably more active than their homogeneous counterparts.

 
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