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Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties

作者	Regan, CF; Guo, ZQ; Chen, YS; Huang, CQ; Chen, M; Jiang, WL; Rueter, JK; Coon, T; Chen, C; Saunders, J; Brown, MS; Betz, SF; Struthers, RS; Yang, C; Wen, J; Madan, A; Zhu, YF

选自	期刊 Bioorganic & Medicinal Chemistry Letters; 卷期 2008年18-16; 页码 4503-4507

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[摘要]：A novel series of potent zwitterionic uracil GnRH antagonists were discovered that showed reduced liability for CYP3A4 enzyme inhibition. (c) 2008 Elsevier Ltd. All rights reserved.
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