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Synthesis and antiproliferative activity of unnatural enantiomers of 7-epi-goniofufurone and crassalactone C

  作者 Popsavin, V; Benedekovic, G; Sreco, B; Popsavin, M; Francuz, J; Kojic, V; Bogdanovic, G  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2008年18-19;  页码  5178-5181  
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[摘要]A facile synthesis of 7-epi-(-)-goniofufurone as well as the first synthesis of (-)-crassalactone C was achieved starting from D-xylose. A comparison of their in vitro antitumour activities with those observed for the corresponding naturally occurring enantiomers was provided. (C) 2008 Elsevier Ltd. All rights reserved.

 
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