【文章名】A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods
A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods
作者
Hernandez-Folgado, L; Schmuck, C; Tomic, S; Piantanida, I
[摘要]:At micromolar concentrations and equimolar conditions in respect to basepairs, a novel pyrene-guanidiniocarbonyl-pyrrole cation 1 exhibited a strong ICD signal at about lambda = 300 nm specifically upon the interaction with ds-DNA, while under the same conditions a new fluorescence maximum at lambda = 480 nm appeared exclusively upon the addition of ds-RNA. (C) 2008 Elsevier Ltd. All rights reserved.