[摘要]:A novel type of gas chemical sensor is fabricated by combining microfabrication techniques and electrochemical transducer. The microchannel sensor we built is composed of liquid/gas microchannels separated by a nanoporous membrane. When oxime chemistry is adapted into it, the microchannel sensor gives response. of hundreds of mV to trace vapor (10 ppb) of acetylcholine simulant within similar to 10 s. Double microchannel design further reduces potential drift and simplifies the sensor setup.