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New Antioxidant Phenolic Glucosides from Viburnum dilatatum

  作者 Wu, B; Wu, SW; Qu, HB; Cheng, YY  
  选自 期刊  Helvetica Chimica Acta;  卷期  2008年91-10;  页码  1863-1870  
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[摘要]Chemical investigation of the fruits of Viburnum dilatatum THUNB. resulted in the isolation and characterization of four new phenolic glycosides, jiamiziosides A-D (1-4), together with five known compounds. Their structures were established by spectroscopic means and by comparison with the literature values. The antioxidant activities of the new isolates were determined against 2,2-diphenyl-1-picrylhydrazyl (=2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazinyl; DPPH) and superoxide radicals. Among the compounds tested, jiamizioside C (3) possesses the most potent inhibitory scavenging effect on DPPH and superoxide radicals with IC50 values of 16.8 and 17.8 mu m, respectively.

 
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