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Live or let die: E2F1 and PI3K pathways intersect to make life or death decisions

  作者 Dyniacht, BD  
  选自 期刊  Cancer Cell;  卷期  2008年13-1;  页码  1-2  
  关联知识点  
 

[摘要]In the current issue of Cancer Cell, Hallstrom et al. show that a subset of targets of the growth regulatory transcription factor E2F1 are repressed by a serum-induced PI3K activation, explaining how apoptosis can be suppressed while simultaneously engaging a proliferation program.

 
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