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Cytotoxic Spirostane-Type Saponins from the Roots of Chlorophytum borivilianum

  作者 Acharya, D; Mitaine-Offer, AC; Kaushik, N; Miyamoto, T; Paululat, T; Mirjolet, JF; Duchamp, O; Lacaille-Dubois, MA  
  选自 期刊  Journal of natural products;  卷期  2009年72-1;  页码  177-181  
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[摘要]Four new spirostane-type saponins named borivilianosides E-H (1-4) were isolated from an ethanol extract of the roots of Chlorophytum borivilianum together with two known steroid saponins (5 and 6). The structures of 1-4 were elucidated using mainly 2D NMR spectroscopic techniques and mass spectrometry. The cytotoxicity of borivilianosides F (2), G (3), and H (4) and three known compounds was evaluated using two human colon cancer cell lines (HT-29 and HCT 116).

 
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