Counting Motors by Force

[摘要]：Properties of the microtubule motor protein kinesin-1 have been well characterized in vitro but not in the viscous environment of a cell. By measuring the force that kinesin-1 exerts on lipid droplets in fly embryos, Shubeita et al. ( 2008) determine the number of active motors per droplet and find unexpected differences between motor regulation in vivo and in vitro.

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