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Nanoscale Increases in CD2-CD48-mediated Intermembrane Spacing Decrease Adhesion and Reorganize the Immunological Synapse

  作者 Milstein, O; Tseng, SY; Starr, T; Llodra, J; Nans, A; Liu, ML; Wild, MK; van der Merwe, PA; Stokes, DL; Reisner, Y; Dustin, ML  
  选自 期刊  Journal of Biological Chemistry;  卷期  2008年283-49;  页码  34414-34422  
  关联知识点  
 

[摘要]The relationship between intermembrane spacing, adhesion efficiency, and lateral organization of adhesion receptors has not been established for any adhesion system. We have utilized the CD2 ligand CD48 with two (wild type CD48 (CD48-WT)), four (CD48-CD2)

 
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