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作者 |
Wong, SL; Chang, HS; Wang, GJ; Chiang, MY; Huang, HY; Chen, CH; Tsai, SC; Lin, CH; Chen, IS |
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[摘要]:Bioassay-guided fractionation of the roots of Neolitsea daibuensis afforded three new beta-carboline alkaloids, daibucarbolines A-C (1-3), three new sesquiterpenoids, daibulactones A and B (4 and 5) and daibuoxide (6), and 20 known compounds. The structures of 1-6 were determined by spectroscopic analysis and single-crystal X-ray diffraction. Daibucarboline A (I), isolinderalactone (7), 7-O-methylnaringenin (8), and prunetin (9) exhibited moderate iNOS inhibitory activity, with IC(50) values of 18.41, 0.30, 19.55, and 10.50 mu M, respectively. |
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