A One-Pot Preparation of 5-Oxo 2,4-Disubstituted 2,5-Dihydro-1H-imidazol-2-carboxylates from alpha-Bromo Esters

[摘要]：Nucleophilic substitution of a bromine atom by the azide group in aryl- and heteroaryl-alpha-bromoacetates triggers cascade reactions leading to imidazolin-5-ones formation. The alpha-azidoacetate intermediates undergo a transformation into non-isolable 2-imino esters that dimerize giving the heterocyclic imidazoline system. The process described is strongly promoted by dipolar aprotic solvents (DMF, DMSO) and could be realized under base- and metal-free conditions.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内