SYNTHESIS OF VARIOUS SUBSTITUTED SPIRO- AND BICYCLETHIAZOLIDINE-2-THIONES BY A MULTICOMPONENT REACTION AND BIOLOGICAL EVALUATION IN VITRO

[摘要]：A series of novel spiro[4.4] and bicycle[3.3.0]-N-substituted thiazolidine-2-thiones were obtained by a multicomponent reaction under mild conditions. Each of the synthesized compounds was evaluated for their cytotoxic activity and antibacterial activity. Some of them exhibited significantly inhibited proliferation of human tumor cell lines and moderate inhibitory effect on fungi.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内