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Highly Efficient Asymmetric Conjugate Additions of Aldehydes with Vinyl Sulfones Using a Sulfonamide Organocatalyst

  作者 MIURA TSUYOSHI; YUASA HIROKI; MURAHASHI MIHO; INA MARIKO; NAKASHIMA KOSUKE; TADA NORIHIRO; ITOH AKICHIKA  
  选自 期刊  SYNLETT;  卷期  2012年-16;  页码  2385-2388  
  关联知识点  
 

[摘要]A sulfonamide organocatalyst promotes the asymmetric conjugate addition of branched aldehydes to vinyl sulfones to afford the corresponding adducts with all-carbon quaternary stereocenters in excellent yields with up to 95% ee.

 
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