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Microwave-Assisted One-Pot Synthesis of Pyrazolo[3,4-b]indoles and New Isoxazolo[5,4-b]indoles via Copper-Catalyzed Intramolecular C-N/C-O Bond Formation

  作者 KUMAR AREPALLI SATEESH; RAO P V AMULYA; NAGARAJAN RAJAGOPAL  
  选自 期刊  Synthesis;  卷期  2011年-23;  页码  3878-3886  
  关联知识点  
 

[摘要]A facile one-pot, two-step synthesis of highly substituted pyrazolo[3,4-b] indoles and isoxazolo[5,4-b] indoles was developed via microwave-assisted, copper-catalyzed intramolecular heterocyclization (involving C-N/C-O bond formation) from 3-acetyl-2-chloroindoles in good to excellent yields.

 
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