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D-Gluco-hept-2-ulose and Novel Deoxyfluoro Derivatives as Seven-Carbon Analogues of F-Deoxy-D-glucose (FDG)

  作者 LESHCH YEVGENIY; WASCHKE DANIEL; THIMM JULIAN; THIEM JOACHIM  
  选自 期刊  Synthesis;  卷期  2011年-23;  页码  3871-3877  
  关联知识点  
 

[摘要]Ketoheptoses, seven-carbon sugars, were recognized to display pharmacological properties that are potentially suitable for in vivo diagnostic of diabetes and cancers using (19)F-MRI. The present paper describes efficient syntheses towards ketoheptoses and exemplary a series of regioisomeric fluoro derivatives of D-gluco-hept-2-ulose.

 
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