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Multiple regio- and chemoselective functionalizations of pyrimidine derivatives using TMPMgCl譒iCl and TMP2Mg? LiCl.

  作者 Mosrin, Marc;Petrera, Marilena;Knochel, Paul;  
  选自 期刊  Synthesis;  卷期  2008年-22;  页码  3697-3702  
  关联知识点  
 

[摘要]The multiple successive regio- and chemoselective magnesiation of com. available 2-bromopyrimidine at the C4, C6, and C5 positions allows the regioselective functionalization of all positions of the pyrimidine ring.

 
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