No-carrier-added [F-18]fluoroarenes from the radiofluorination of diaryl sulfoxides

[摘要]：No-carrier-added [F-18]fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [F-18]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4-[F-18]fluoroarenes in high RCYs. This process broadens the scope for preparing novel F-18-labeling synthons and PET radiotracers.

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