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Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution

  作者 Holt, LJ; Tuch, BB; Villen, J; Johnson, AD; Gygi, SP; Morgan, DO  
  选自 期刊  Science;  卷期  2009年325-5948;  页码  1682-1686  
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[摘要]To explore the mechanisms and evolution of cell-cycle control, we analyzed the position and conservation of large numbers of phosphorylation sites for the cyclin-dependent kinase Cdk1 in the budding yeast Saccharomyces cerevisiae. We combined specific che

 
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