个性化文献订阅>期刊> Journal of natural products
 

HPLC-ESIMSn Profiling, Isolation, Structural Elucidation, and Evaluation of the Antioxidant Potential of Phenolics from Paepalanthus geniculatus

  作者 do Amaral, FP; Napolitano, A; Masullo, M; dos Santos, LC; Festa, M; Vilegas, W; Pizza, C; Piacente, S  
  选自 期刊  Journal of natural products;  卷期  2012年75-4;  页码  547-556  
  关联知识点  
 

[摘要]The methanol extract of the flowers of Paepalanthus geniculatus Kunth. showed radical-scavenging activity in the TEAC assay. An analytical approach based on HPLC:ESIMSn was applied to obtain the metabolite profile of this extract and led to the rapid identification of 19 polyphenolic compounds comprising flavonoids and naphthopyranones. The new naphthopyranone (10, 16), quercetagetin (1, 5, 7, 13), and galetine derivatives (9, 11, 17, 19), and a flavonol glucoside cyclodimer in the truxillate form (12), were identified. Compounds 2, 6, and 7 showed the highest antioxidant capacity and ability to affect the levels of intracellular ROS in human prostate cancer cells (PC3).

 
      被申请数(0)  
 

[全文传递流程]

一般上传文献全文的时限在1个工作日内