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Silver- and Gold-Catalyzed Intramolecular Rearrangement of Propargylic Alcohols Tethered with Methylenecyclopropanes: Stereoselective Synthesis of Allenylcyclobutanols and 1-Vinyl-3-oxabicyclo[3.2.1.]octan-8-one Derivatives

  作者 YAO LIANGFENG; WEI YIN; SHI MIN  
  选自 期刊  Journal of Organic Chemistry;  卷期  2009年74-24;  页码  9466-9469  
  关联知识点  
 

[摘要]Ag(I)-catalyzed intramolecular reaction of monoarylmethylenecyclopropanes (MCPs) tethered with 1,1,3-triarylprop-2-yn-1-ols provides diastereoselective access to polysubstituted allenylcyclobutanols and the obtained allenylcyclobutanols catalyzed by Au(I) furnish a wide range of bridged bicyclic compounds with a vinyl-substituted quaternary stereogenic center stereo selectively.

 
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