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Efficient and Practical Synthesis of 5 '-Deoxytubercidin and Its Analogues via Vorbruggen Glycosylation

  作者 SONG YANG; DING HAIXIN; DOU YANHUI; YANG RUCHUN; SUN QI; XIAO QIANG; JU YONG  
  选自 期刊  Synthesis;  卷期  2011年-9;  页码  1442-1446  
  关联知识点  
 

[摘要]An efficient and practical synthesis of naturally occurring marine nucleosides 5'-deoxytubercidins on a 10 gram scale in good overall yield is reported. The key step was the Vorbruggen glycosylation of pyrrolo[2,3-d]pyrimidines with 5-deoxy-1,2,3-tri-O-acetyl-beta-D-ribofuranose.

 
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