[摘要]:In this article we proved that all three key steps in the catalytic cycle of CuAAC can proceed in the presence of carboxylic acids and the latter two steps can be promoted significantly by carboxylic acids Benzoic acid showed the best promotion activity and the acids with strong chelaung ability to Cu(I) ion could not serve or this purpose Thus. the first carboxylic acid-promoted highly efficient CuAAC was established |