Regioselective Cross-Coupling Reactions of Boronic Acids with Dihalo Heterocycles

[摘要]：The carboxylic acid anion moiety have been used as a tunable directing group in the cross-coupling reaction of 2 6-dichloronicotinic acid and 2,5-dibronio-1,2,4-triazole derivatives producing selectively the 2- or 6-substituted nicotinic acids, while only the 5-substituted triazoles were obtained nuclei a variety of conditions

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