SYNTHESIS OF NOVEL 5-(PYRIMIDIN-5-YL)-1,2,4-OXADIAZOLE DERIVATIVES VIA A THREE-COMPONENT CYCLOADDITION AND SUBSEQUENT OXIDATIVE DEHYDROGENATION
[摘要]:A new and efficient strategy has been developed for the synthesis of novel 5-(pyrimidin-5-yl)-1,2,4-oxadiazoles with a wide diversity in substituents via Biginelli cycloaddition and subsequent oxidative dehydrogenation.
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