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Benzylic carbon oxidation by an in situ formed o-iodoxybenzoic acid (IBX) derivative.

  作者 Ojha, Lawanya R.;Kudugunti, Shashi;Maddukuri, Padma P.;Kommareddy, Amitha;Gunna, Meena R.;Dokuparthi, Praveen;Gottam, Hima B.;Botha, Kiran K.;Parapati, Divya R.;Vinod, Thottumkara K.;  
  选自 期刊  SYNLETT;  卷期  2009年-1;  页码  117-121  
  关联知识点  
 

[摘要]A review. Benzylic C-H bonds are selectively oxidized to the corresponding carbonyl functionalities using catalytic quantities of 2-iodobenzoic acid (2IBAcid) and Oxone. The reported procedure tolerates different functional groups and operates under mild conditions. A radical mechanism is proposed for the transformation and evidence supporting the proposed mechanism is also presented.

 
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