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Total synthesis of arylomycin A2, a signal peptidase I (SPase I) inhibitor.

  作者 Dufour, Jeremy;Neuville, Luc;Zhu, Jieping;  
  选自 期刊  SYNLETT;  卷期  2008年-15;  页码  2355-2359  
  关联知识点  
 

[摘要]A concise total synthesis of arylomycin A2 was accomplished featuring a key intramol. Suzuki-Miyaura reaction for the formation of the 14-membered meta,meta-cyclophane and direct coupling of a fully elaborated peptide side-chain with the macrocyclic core.

 
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