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Atomic View of a Toxic Amyloid Small Oligomer

  作者 Laganowsky, A; Liu, C; Sawaya, MR; Whitelegge, JP; Park, J; Zhao, ML; Pensalfini, A; Soriaga, AB; Landau, M; Teng, PK; Cascio, D; Glabe, C; Eisenberg, D  
  选自 期刊  Science;  卷期  2012年335-6073;  页码  1228-1231  
  关联知识点  
 

[摘要]Amyloid diseases, including Alzheimer's, Parkinson's, and the prion conditions, are each associated with a particular protein in fibrillar form. These amyloid fibrils were long suspected to be the disease agents, but evidence suggests that smaller, often

 
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