Tetrahydropyridinium bromide: Useful synthon to functionalized pyrrolidines

[摘要]：1-benzyl-5-(ethoxycarbonyl)-2,3,4,5-tetrahydropyridinium bromide undergoes ring contraction with a series of nucleophiles, getting 2,2-disubstitued pyrrolidines. Moreover, from some of the new 2,2-disubstitued pyrrolidines were synthesized spiro-pyrrolidines. J. Heterocyclic Chem.,(2011).

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