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[摘要]:A selective method for the synthesis of 3-iodo-1,5-benzothiazepin-4-ones via the intramolecular iodocyclization of N-[2-(methylthio)phenyl]propiolamides has been developed. In the presence of I-2, iodocyclizations of N-[2-(methylthio)phenyl]propiolamides were conducted smoothly to afford the corresponding 3-iodo-1,5-benzothiazepin-4-ones in moderate to good yields. |
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