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One-Step Synthesis of Highly Functionalized Monofluorinated Cyclopropanes from Electron-Deficient Alkenes

  作者 IVASHKIN PAVEL; COUVEBONNAIRE SAMUEL; JUBAULT PHILIPPE; PANNECOUCKE XAVIER  
  选自 期刊  Organic Letters;  卷期  2012年14-9;  页码  2270-2273  
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[摘要]The unique combination of Zn/LiCl allowed generation of reactive zinc enolate from ethyl dibromofluoroacetate. This fluorinated enolate reacts efficiently with a wide range of functionalized electron-deficient alkenes to afford the corresponding monofluorinated cyclopropylcarboxylates in good yields.

 
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