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Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity

  作者 Gajewski, MP; Beall, H; Schnieder, M; Stranahan, SM; Mosher, MD; Rider, KC; Natale, NR  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2009年19-15;  页码  4067-4069  
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[摘要]Dimeric analogs of Anthracenyl Isoxazole Amides (AIMs) (the designation AIM is in honor of the memory of Professor Albert I. Meyers) were prepared and dimer 6 exhibited the highest efficacy to date for this class of anti-tumor compounds against the human glioma Central Nervous System cell line SNB-19. (C) 2009 Elsevier Ltd. All rights reserved.

 
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