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MICROWAVE-ASSISTED SYNTHESIS OF 3,5-DISUBSTITUTED THIOHYDANTOINS USING FUNCTIONAL IONIC LIQUID AS SOLUBLE SUPPORT

  作者 ZHUO CHEN; XIAN DONG; HUI XIE; MEI LI  
  选自 期刊  Heterocycles;  卷期  2011年83-5;  页码  1121-1127  
  关联知识点  
 

[摘要]A new approach for the syntheses of 3,5-disubstituted thiohydantoins was described using functionalized ionic liquid as soluble support. The products were obtained in good yields and purities after cyclization-cleavage from the ionic-liquid-supported under microwave irradiation, the ionic-liquid-supported species can there be purified from the reaction mixture by simple washing, and no chromatographic purification were needed during the synthesis.

 
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