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Dihydropyrazolopyrimidine Inhibitors of K(V)1.5 (I-Kur)

  作者 Vaccaro, W; Huynh, T; Lloyd, J; Atwal, K; Finlay, HJ; Levesque, P; Conder, ML; Jenkins-West, T; Shi, H; Sun, L  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2008年18-24;  页码  6381-6385  
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[摘要]A series of dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I-Kur) have been identified. The synthesis, structure-activity relationships and selectivity against several other ion channels are described. (C) 2008 Elsevier Ltd. All rights reserved.

 
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