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alpha-S-GalCer: Synthesis and evaluation for iNKT cell stimulation

  作者 Blauvelt, ML; Khalili, M; Jaung, W; Paulsen, J; Anderson, AC; Wilson, SB; Howell, AR  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2008年18-24;  页码  6968-6970  
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[摘要]The synthesis and evaluation for iNKT stimulation of alpha-S-galactosylceramide is reported. Prepared by alkylation of a galactosylthiol, this analog of the potent immunostimulatory agent, KRN7000, did not stimulate iNKT cells either in vitro or in vivo. (C) 2008 Elsevier Ltd. All rights reserved.

 
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