Biased Signaling Pathways in beta(2)-Adrenergic Receptor Characterized by F-19-NMR

[摘要]：Extracellular ligand binding to G protein-coupled receptors (GPCRs) modulates G protein and beta-arrestin signaling by changing the conformational states of the cytoplasmic region of the receptor. Using site-specific F-19-NMR (fluorine-19 nuclear magnetic

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