A General and Facile Synthesis of Novel Polysubstituted Quinazolin-4(3H)-ones

[摘要]：A simple and efficient approach to synthesize novel polysubstituted quinazolin-4(3H)-ones has been developed, and the key step is a sequential procedure involved iron-mediated reduction and acid-catalytic cyclization. The present method provides a convenient and practical strategy for the synthesis of quinazolin-4(3H)-one derivatives.

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