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A convenient one-pot preparation of N-substituted 4-phenylpiperidines.

  作者 Asano, Shigehiro;Ban, Hitoshi;  
  选自 期刊  Heterocycles;  卷期  2008年75-1;  页码  183-188  
  关联知识点  
 

[摘要]N-Substituted 4-phenylpiperidines were readily synthesized by one-pot cyclization of diols with amines via bis-triflate intermediates. The new synthesis under mild conditions gave various N-substituted 4-phenylpiperidines in moderate to good yields.

 
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