Versatile Synthesis of 1-O-(omega-Aminolauryl)-I(4,5)P2

[摘要]：The synthesis of a model 1-O-(?-aminoacyl)-IP2 derivative, lauryl 4,5-bisphosphate 31, was realized following a versatile and high-yielding scheme. The flexible synthetic strategy used for this purpose allows the preparation of a range of other useful IP, IP2 and IP3 derivatives. In view of the central role played by IPs and PIPs in cellular life, the preparation of functionalized myo-inositol derivatives of this type may facilitate the isolation and fluorescent localization of related proteins.

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